In 2002 Entertainment Weekly included Eduardo Rodriguez on its "It List" of the 100 Most Creative People in Entertainment. In 2005, he completed his first feature film, Curandero, which was written and executive produced by Robert Rodriguez (Alita). In 2006, Sam Raimi (Spider-Man) contacted Eduardo to create and direct several new scenes for The Messengers. The film was released by Screen Gems and ended its domestic run with a total gross of 35M US$. In 2009, Eduardo helmed The Circle, an episode of the NBC horror anthology Fear Itself. In 2011, he directed two movies consecutively for After Dark Films and Silver Pictures: El Gringo with Christian Slater and Stash House with Dolph Lundgren. In 2013, he directed and co-edited Fright Night 2, starring Jaime Murray (Dexter), for Twentieth Century Fox. In 2019, Eduardo edited and directed his first indie film, You're Not Alone, starring Katia Winter (Sleepy Hollow). In 2020, Eduardo wrote, directed and co-edited The Darkness of the Road, starring Najarra Townsend (Tru Loved) and Johnny Whitworth (Ghost Rider: Spirit of Vengeance), which will be released on VOD in Dec 2021.